Innovation from experience

Clinically evaluated protocol

XEROSKIN

An Integrated Medical Protocol for the Management of Xerosis and Very Dry Skin

The Xeroskin program combines professional in-office treatment with continuous home-care maintenance, two complementary and inseparable phases.

  • Controlled exfoliation
  • Intensive rehydration
  • Barrier repair
  • Long-term maintenance
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Xeroskin professional protocol and home-care product range

Clinically evaluated protocol for improving skin barrier function in Dry and Very Dry Skin

Woman touching her face against a light blue background

Dry skin and xerosis cutis are highly prevalent conditions characterized by impaired skin barrier function, reduced stratum corneum hydration, and increased transepidermal water loss (TEWL).

While frequently affecting the face, xerosis commonly involves other areas such as the neckline, hands, and legs, significantly impacting skin comfort and quality.

The INNOAESTHETICS Xeroskin protocol has been specifically designed to restore barrier function, rebalance the hydrolipidic mantle, and improve the skin’s ability to retain water, addressing xerosis at its origin rather than masking symptoms.

Clinical and Biological Features of Xerosis

Clinically, xerotic skin presents with roughness, scaling, reduced elasticity, impaired skin comfort, sensations of tightness or irritation, and increased sensitivity to environmental factors, reflecting a progressive loss of barrier integrity and hydration capacity.

From a Biological Standpoint, Xerosis Is Primarily Driven By:

Xeroskin professional protocol and home-care products
  • Depletion of epidermal lipids, particularly ceramides
  • Reduced levels and altered composition of Natural Moisturizing Factor (NMF)
  • Increased transepidermal water loss (TEWL)
  • Structural alterations of the stratum corneum and impaired corneocyte cohesion

These mechanisms compromise the skin’s ability to retain water and protect against external aggressors, perpetuating a cycle of dryness, barrier damage, and reduced skin resilience.

Effective management therefore requires an integrated medical approach addressing these underlying mechanisms through controlled exfoliation, intensive rehydration, barrier repair, and long-term maintenance of skin homeostasis.

Xeroskin Protocol

The Xeroskin program combines professional in-office treatment with continuous home-care maintenance, two complementary and inseparable phases. It can be applied to both facial and body areas affected by xerosis.

1 Month
Professional phase

The Xeroskin Medical Protocol

Standard Treatment

4 sessions at 7-day intervals alternating peel and transdermal treatment.

1st Session 1 week
Keratoderm treatment product
2nd Session 1 week
Xeroskin-ID transdermal treatment
3rd Session 1 week
Keratoderm treatment product
4th Session
Xeroskin-ID transdermal treatment

Intensive Protocol

4 sessions at 7-day intervals combining peel and transdermal treatment in the same session.

1st Session 1 week
Keratoderm treatment product Xeroskin-ID transdermal treatment
2nd Session 1 week
Keratoderm treatment product Xeroskin-ID transdermal treatment
3rd Session 1 week
Keratoderm treatment product Xeroskin-ID transdermal treatment
4th Session
Keratoderm treatment product Xeroskin-ID transdermal treatment
3 Months
Home phase

Home-Care Maintenance

Long-term results require continuous home care to prevent relapse. Recommended use: before, during, and after the in-office protocol.

Day Routine

Xeroskin Day Cream
Keratoderm
  • INNO DERMA® Xeroskin Day Cream: Hydration, comfort, and protection.
  • INNO DERMA® Keratoderm: Supports desquamation and skin flexibility.

Night Routine

Xeroskin Night Cream
Keratoderm
  • INNO DERMA® Xeroskin Night Cream: Barrier repair with ceramides and NMF agents.
  • INNO DERMA® Keratoderm: Supports desquamation and skin flexibility.

Clinically Proven Results

Representative images showing improvement in skin surface structure and hydration.

Representative skin surface before treatment
Before
Representative skin surface after treatment
After
Instrumentally Measured

Key Clinical Results

−23.3%

Mean Reduction in TEWL

Up to −51.8%

+17.2%

Mean Increase in Skin Elasticity

Up to +56%

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Bring XEROSKIN to your practice

Discover an integrated in-clinic and home-care protocol for dry and very dry skin. Complete the form to learn more about its professional application.

INNOAESTHETICS

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