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Logo Meline

Solar lentigo is a common skin problem that affects a high range of people after forty worldwide. It is a benign lesion that manifests in the form of a rounded dark spot or patch on the skin. Although well-defined, it can have irregular shapes. We usually find more than one, or clusters of them, in the most sun-exposed skin areas. They (solar lentigines in plural) appear with age, as a result of cumulative sun exposure. Most people associate them with aging and make them feel older. In fact, solar lentigo is considered a sign of skin photoaging.

Solar lentigines appear most prominently on the face, neckline, and back of the hands. They are known by different names – age spots, dark spots, liver spots.

Nowadays, several types of therapies and techniques can attenuate them or make them disappear completely – chemical peels and laser being the most effective ones. However, achieving the best possible results can be a challenge, and the expertise of reliable skin experts and high-quality products are required.


MELINE® is the only brand specializing in the treatment of skin hyperpigmentation. It provides professionals with an extensive range of products that effectively even the skin tone, regardless of the type of pigmentation problem and the skin phototype. For the treatment of solar lentigo, we recommend a depigmenting kit that comprises a professional treatment to apply in-office and a follow-up at home. The number of treatment sessions, time for the follow-up, and the outcome expectations can vary according to hyperpigmentation severity, skin type, phototype, skin tolerance and response.


MELINE® SPOTS has been specially designed to fade solar lentigines.  It includes a professional kit and a home-use product in the form of a roll-on for the follow-up.


The kit includes a first solution of tyrosinase-inhibitors and a second depigmenting solution that promotes skin exfoliation, re-epithelialization, and cell turnover. The ingredients contained in these two formulas act on all the stages of hyperpigmentation to effectively fade it and prevent its recurrence. One session in-office, accompanied by the follow-up at home with MELINE® 02 SPOTS, is usually enough to fade the solar lentigo. Nevertheless, more sessions could be required, according to the patient’s needs and professional judgment.

  • STEP 1: It acts in the early stages of solar lentigo and prevents the risk of a rebound effect. The main goal of this solution is to control tyrosinase activity to prevent melanin overproduction. Tyrosinase is the enzyme that catalyzes the production of melanin.

Therefore, it is mainly composed of tyrosinase-inhibitors: Tranexamic Acid, Azelaic Acid, Resorcinol, among other ingredients.

Tranexamic Acid inhibits UV-induced plasmin activity in keratinocytes – primary cell in the epidermis. This effect ultimately leads to a reduction of arachidonic acid and prostaglandin production, which are tyrosinase stimulators. Hence, decreasing tyrosinase activity. It lightens the skin and prevents future hyperpigmentation.

Azelaic Acid has many benefits and can be used to treat different skin alterations. Among them, it is a good free radical scavenger, which means that it has antioxidant properties, and has proven to lighten hyperpigmentation. Like tranexamic Acid, it helps to inhibit the action of the tyrosinase enzyme.

Resorcinol has a high tyrosinase-inhibitory capacity on human skin and has shown spectaculars results in the removal of all types of hyperpigmentation.

The combination of these three tyrosinase-inhibitors fades the existing pigmentation problem and paves the path for the next solutions to achieve unbeatable results.

  • STEP 2: This second step is made of superficial peeling agents that provide strong depigmenting effects while also helping to renew and re-balance the skin.

Among its ingredients, we find Pyruvic and Salicylic Acid.

Pyruvic Acid works in both the epidermis and the dermis, helping to remove hyperpigmentation from the deepest layers to the uppermost. Moreover, it regulates collagen, elastic fiber, and glycoprotein synthesis.

Salicylic Acid is a recognized, safe, and well-tolerated agent to promote skin exfoliation and even skin tone. It gently breaks down the upper layer of the skin tissue, thus promoting, in turn, skin renewal. It effectively lightens dark spots and leaves the skin softer and brighter.

Meline spots 01

Home use skincare product that reinforces the effects of the professional treatment and helps to achieve long-lasting results. This follow-up at home is essential for the success of the treatment.

MELINE® 02 SPOTS is a roll-on that can be very easily applied by the patient on the affected areas. Its active ingredients work in synergy to regulate melanin synthesis and prevent damage from UV-induced Reactive Oxygen Species (ROS) and Nitrogen. Therefore, this solution effectively provides a sustained action that optimizes the effects of the above-mentioned professional treatment.

Meline Spots 02

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